In the absence of the enzyme of interest, the soluble off-probes are permanently silent; they do not emit any detectable background signal.

The probe’s conversion by the target enzyme results in the release of a bright yellow-green and extremely photostable fluorescent precipitate retained in the cell.

Fast and easy protocols offering end to end compatibility under physiological conditions: just mix and get what you’re screening for.

The only robust fluorogenic precipitation-based probes commercially available:

loupe
Enhanced Sensitivity
plus-button
No False Positives
unlink
Signal Retention
 
 
thunder
Fast Results
thumb
Easy to Use
cog
Versatile Technology

Our partners